
Indianapolis has evolved into one of the Midwest's most vibrant tech hubs, with a unique ecosystem that balances established enterprise companies, innovative startups, and strong community support networks. As of June 2025, the tech landscape continues to evolve rapidly, with several key developments shaping its future.
Key Players in the Indianapolis Tech Ecosystem
Enterprise Leaders
- Salesforce Indianapolis: Following their continued expansion in the Salesforce Tower, they've launched new AI initiatives focused on customer experience automation, employing over 2,500 tech professionals locally.
- Eli Lilly Digital: Their tech division has grown substantially, focusing on AI-driven drug discovery and digital health solutions, becoming a major tech employer beyond traditional pharma.
- Cummins Digital Accelerator: The traditional manufacturing giant has transformed its digital division into a powerhouse for IoT and sustainable energy tech solutions.
- Genesys Cloud: Has expanded their Indianapolis presence with their cloud customer experience platform, now employing over 1,000 tech professionals in the region.
Emerging Scale-ups
- HighAlpha Portfolio Companies: The venture studio continues to launch successful B2B SaaS companies, with recent successes in fintech and healthcare AI applications.
- Lessonly by Seismic: Has continued growing their learning platform with new AI capabilities, becoming a centerpiece of the local tech education ecosystem.
- Zylo: The SaaS management platform has reached unicorn status after their latest funding round, highlighting Indy's strength in enterprise software.
- Malomo: The shipment tracking platform has expanded internationally, showcasing Indy's e-commerce tech capabilities.
Promising Startups
- GreenTech Indy: A climate tech startup cluster has formed around 16 Tech, focusing on sustainable energy solutions.
- MedTech Mile: The healthcare technology corridor has attracted numerous startups working on telehealth and remote patient monitoring.
- Fintech Collective: A new collaborative of financial technology startups has emerged downtown, supported by local banking institutions.
Innovation Hubs and Community Resources
- 16 Tech: The innovation district has fully matured, hosting over 75 tech companies and becoming the physical center of the tech ecosystem.
- The Union 525: Continues to serve as a tech hub with expanded programming for early-stage startups.
- Innovation Mile: The corridor connecting downtown to 16 Tech has developed into a continuous innovation zone.
- TechPoint: The growth accelerator for Indiana's tech ecosystem has launched new initiatives to attract remote workers to relocate to Indianapolis.
Looking Ahead
As Indianapolis continues to evolve as a tech hub, the focus on specialized sectors like enterprise SaaS, healthtech, and agtech provides a strong foundation for sustainable growth. The collaborative nature of the ecosystem, combined with strategic public-private partnerships, positions Indianapolis well for continued tech sector expansion throughout 2025 and beyond.